Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 15th International Conference on Nephrology and Hypretension Istanbul,Turkey .

Day 2 :

  • Clinical Trials and Case Reports | Glomerulonephritis | Pediatric Nephrology | Chronic Kidney Disease
Location: Istanbul, Turkey

Chair

Punit Gupta

Sharda University, India

Session Introduction

Ahmad Makeen

Ministry of National Guard Health Affairs, Saudi Arabia

Title: Willingness of hemodialysis patient’s family members toward kidney donation: A cross sectional study
Biography:

Ahmad Makeen Senior Internal Medicine Resident King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia. 

Abstract:

Background & Objectives: There is a significant shortage of kidneys available for donation. Family members of Hemodialysis (HD) patients are experiencing the suffering of their close relatives, which can be a factor toward better acceptance to kidney donation. The knowledge is another important factor that might affect willingness, it was found in a study conducted in Nigeria that the presence of desirable knowledge about organ donation will influence the rate of willingness and in another study where educational intervention done, they found this approach significantly improves the knowledge and changes the attitude and beliefs towards organ donation. We aimed in this study to estimate the rate of willingness to donate kidneys as Live Donors (LD) and identify related potential barriers among family members of HD patients. Methods: A cross-sectional observational study involving family members of adult HD patients from King Abdulaziz Medical City and King Abdullah International Foundation- Dialysis Project-Jeddah. Participants were interviewed through phone calls using a pre-tested questionnaire. Calculated sample size was 385. Results: A total of 370 family members of HD patients were included. Median age was 37 (IQR: 33 to 44) years and 64% were male. All participants were first-degree relatives to HD patients. Majority reported willingness to donate kidneys as LD (n=300, 81%), a proportion 0.81% with 95% Confidence Interval [CI], 0.77-0.85. Only 42 (11%) graded their knowledge about kidney transplantation as high or very high. On multivariable analysis, less willingness was shown with age >40 years (Adjusted Odds Ratio [AOR] 0.459; 95% CI 0.2660.792; P 0.005) and female gender (AOR 0.496; 95% CI 0.287-0.856; P 0.012). Conclusion: Majority of family members of HD patients were willing to donate kidneys. The willingness rate was lower among participants 40 years of age and older as well as among female gender. Majority of patients graded their knowledge about kidney transplantation as average or lower. Therefore, education-targeting relatives of HD patients may help optimize knowledge and hence improve acceptance of kidney donation.

Imane Failal

University Hospital Center Ibn Rochd- Casablanca, Morocco

Title: Perioperative management of pediatric renal transplantation
Biography:

Imane Failal is a Nephrology Resident at the ibn rochd university and hospital center in Casablanca, Morocco

Abstract:

Introduction & Objective: In kidney transplantation, the immediate per and postoperative period is a critical period for patient and graft survival. The objective of our study is to highlight the different modalities of anaesthesia and resuscitation in the context of the management of renal transplantation from a living donor. Method: We conducted a retrospective study on all kidney transplant patients admitted to the Nephrology Department of Ibn Rochd University Hospital in Casablanca between June 2007 and March 2019 in consultation with the paediatric anaesthesia and paediatric resuscitation Department at Abderrahim El Harouchi Paediatric University Hospital of Casablanca. Results: The age of our patients ranged from 5 to 17 with an average age of 11 years. The sex ratio was 1.2 with 11 boys and 9 girls. Initial nephropathy dominated by congenital malformations. A history of hypertension was found in 45% of patients. The infectious antecedents were found in 45% of the cases. The surgical history was found in 40% of cases. At the time of the transplant, 19 patients had undergone dialysis for at least six months. Renal transplantation was pre-emptive in one patient. Regarding the systemic impact, the majority of our patients had a failure to thrive. All patients underwent a complete clinical examination and further investigations after which dedifferentiated kidneys without other abnormalities on ultrasound found in 80% of patients. Immediate follow-up was simple for 65% of patients. In the medium and long term, 8 patients experienced complications including peritonitis, CMV infection and hemothorax. All these complications have been treated with a good evolution later. Conclusion: A general mobilization must be carried out to establish the infrastructure and the human and technical necessary resources to care children with end-stage of renal failure; this could be accomplished through kidney transplantation, promotion of organ donation to allow patients with chronic renal failure to access to the best treatment that can currently be offered.

Biography:

Sanae Ezzaki has completed her Graduation from the University of Medicine and Pharmacy of Rabat, Morocco. She is currently Resident in Nephrology Hemodialysis at the Ibn Rochd University and Hospital Center in Casablanca, Morocco. 

Abstract:

Introduction: Aortic Aneurysm (AA) is a common pathology in the general population. Subjects at risk are those with risk factors for arterial degeneration including arterial hypertension, smoking and inflammation. Although in chronic renal failure undergoing hemodialysis and especially these risk factors are almost all present, few studies devoted their AA. We report two cases of AA patients receiving hemodialysis. Case-1: A man of 52 years old, antecedent of arterial hypertension for 21 years, reported chronic end-stage renal failure on indeterminate nephropathy in hemodialysis for 15 years. After 6 years of dialysis, it submitted an acute coronary syndrome accompanied by abdominal pain syndrome that led to the diagnosis of an aneurysm of the ascending aorta 5cm in diameter. No treatment was adopted with annual monitoring by CT angiography and preventing thrombosis by platelet antiaggregant. The lesion remains steady until 9 years. Case-2: A man of 42 years old, with no particular history, reported chronic end-stage renal failure on indefinite nephropathy on hemodialysis for 6 years. At its 5th dialysis year he presented abdominal pain and inability to have a bowel movement or pass gas that led to the diagnosis of abdominal aortic aneurysm 4.7 cm in diameter and a height of 12 cm. No treatment was also adopted with surveillance and anti-thrombotic prevention. After 1 year of evolution, the patient had mesenteric ischemia syndrome exploration cracking of the aneurysm that led to his death. Conclusion: AA at chronic kidney disease has been until a few case series that involved most often cases of polycystic kidney disease not yet on dialysis. AA patients receiving hemodialysis is a reality, evolution remains unpredictable sometimes fatal where screening is required.
 

Imane Failal

University Hospital Center Ibn Rochd- Casablanca, Morocco

Title: Quality of life in chronic hemodialysis patients
Biography:

Imane Failal is a Nephrology Resident at the ibn rochd university and hospital center in Casablanca, Morocco 

Abstract:

Objective: The evaluation of quality of life is a new approach to the patient with ESRD. The goal of this work is to investigate the QOL of patients by KDQoL-SF 36 scale Tm and objectify factors influencing this quality. Method: This is a cross observational study conducted between July to September 2019, including 78 chronic hemodialysis patients assessed by a specific questionnaire kidney disease translated and validated in Arabic dialect: KDQoL-SF36 Tm. The socio-demographic and clinical data that may influence QOL were collected from the patient's medical record. The search for predictors of QOL was conducted by a united analysis and multi varied. Results: The average age of patients was 45.78+/-15.20 with a sex ratio 0.92. Over 50% of patients did not have their bachelor's degree and 85.9% unemployed 4% having a stable job and 2.6% more students; causal nephropathy was undetermined in 52.6% of cases. The average length of hemodialysis was 8.34+/-6.07 years and the majority of patients enjoyed three sessions/week. 47% of our patients had anemia. In univariate analysis, the comparative study of the various components of the score found statistically significant association between the mental component of the scoring and age, le niveau study and the socioeconomic level of quality dialysis (Kt/V). For cons, the length of the MR and anemia were associated with greater weight in the RM and the physical component. In multivariate analysis, the presence of CVD has increased the risk of poor QOL on Plan symptoms and consequences of MR and age >60 years has increased the risk of poor QOL. On the contrary, having a profession is a good QOL factor in terms mental and seniority in HD >5 years was positively impacted QOL physically. QOL is a complex concept which results from an interaction of several components, which explains the multiplicity of scales and assessment scores. Conclusion: This study provides an understanding of the factors that are associated with quality of life in HD patients. Low QOL among HD patients is closely associated with a higher risk of morbidity and mortality