Nephrology and Hypertension

Antidiuretics & Antihypertensive Drugs

An antidiuretic is a drug substance that helps to manage fluid balance in human’s body by reducing urination, opposing diuresis. These effects are opposite to diuretic. The main endogenous antidiuretics are antidiuretic hormone also referred as vasopressin & oxytocin. Both of those are used externally as medications in individuals whose bodies require addition help with fluid balance through suppression of diuresis. There are several other antidiuretic drugs, in their some molecularly nearer to anti diuretic hormone or oxytocin and others not. Antidiuretics decreases urine volume, principally in diabetes insipidus. Antihypertensive therapy helps to prevent the difficulties of hypertension also known as hypertension, such as stroke &myocardial infarction. Reduction of the BP (blood pressure) by 5 mmHg can reduces the risk of stroke by 34% & ischaemic heart disease by 21% & decreases the possibilities of heart failure, dementia & mortality from cardiovascular disease. There are several classes of antihypertensives, which reduce blood pressure by different means. Among the most significant and mostly used medications are calcium channel blockers, thiazide diuretics, ACE inhibitors, beta blockers and angiotensin II receptor antagonists.